Antinociceptive effect of Matricaria chamomilla on vincristine-induced peripheral neuropathy in mice
نویسندگان
چکیده
منابع مشابه
Antinociceptive Effect of Memantine and Morphine on Vincristine-induced Peripheral Neuropathy in Rats
BACKGROUND Vincristine-induced peripheral neuropathy is a major dose limiting side effect and thus effective therapeutic strategy is required. In this study, we investigated the antinociceptive effect of memantine and morphine on a vincristine-induced peripheral neuropathy model in rats. METHODS Male Sprague-Dawley rats weighing 220-240 g were used in all experiments. Rats subsequently receiv...
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In this study investigated the effect of putrescine sprayed (0.5 & 1mM) on Chamomile (Matricaria chamomilla L.) and the changed of Anthocyanin, Phenolic compounds, POX & CAT Antioxidative enzymes were examined. The results show that Putrescine treatments increased hydrogen peroxide in seedlings to compare control. Phenolic compound content under putrescine treatments are different. Phenolic com...
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15 صفحه اولeffects of lithium on peripheral neuropathy induced by vincristine in rats
vincristine (vcr) as a frequently used antimitotic agent which is commonly prescribed for wide spectrum of neoplasm, causes mixed sensorimotor neuropathy. several evidences show lithium could be a neuroprotective agent, therefore to assess whether a pretreatment and at subtherapeutic dose it could prevent the peripheral neuropathy produced by vcr, rats were treated with vcr 0.1mg/kg i.p. for 3 ...
متن کاملVincristine-induced peripheral neuropathy in pediatric cancer patients.
Vincristine is a chemotherapeutic agent that is a component of many combination regimens for a variety of malignancies, including several common pediatric tumors. Vincristine treatment is limited by a progressive sensorimotor peripheral neuropathy. Vincristine-induced peripheral neuropathy (VIPN) is particularly challenging to detect and monitor in pediatric patients, in whom the side effect ca...
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ژورنال
عنوان ژورنال: African Journal of Pharmacy and Pharmacology
سال: 2012
ISSN: 1996-0816
DOI: 10.5897/ajpp11.340